Vitamin B6

INCI: Pyridoxine, Pyridoxine Hydrochloride
Category: Vitamin, skin-support nutrient
Used in: Skincare, supplements
Typical Usage Level (Topical):
0.1% – 1% in leave-on skincare formulations

Typical Usage Level (Oral Supplements):
1.3–2 mg per day for general nutritional support
Higher doses may be used under medical guidance.

What This Ingredient Does

Vitamin B6 (pyridoxine) is a water-soluble vitamin involved in multiple metabolic pathways that support healthy skin function. It plays a role in amino acid metabolism and lipid regulation, processes that influence how the skin produces and manages sebum.

Adequate levels of vitamin B6 help support balanced oil production, which can be helpful for individuals experiencing excess sebum or oil-related skin concerns. In skincare and supplements, it is often included as a supportive nutrient for maintaining healthy skin and scalp function.

Vitamin B6 is frequently combined with other skin-support nutrients such as zinc, as both play complementary roles in regulating inflammation and oil balance in acne-prone skin.

Key Benefits

• Helps support balanced sebum production
• Contributes to healthy skin barrier
• Supports healing in acne-prone skin
•  Plays a role in maintaining healthy skin and scalp function
• Supports overall nutritional skin health

Who It’s Best For

• Oily or acne-prone skin
• Individuals experiencing excess sebum production
• People seeking nutritional support for skin balance
• Those managing oil-related scalp concerns

Clinical Note by Dr. Su

M.D. Dermatologist

Vitamin B6 is primarily a supportive nutrient that contributes to balanced skin metabolism and oil regulation. It is most effective when part of a broader nutritional and skincare approach that supports overall skin health.