Vitamin B12

INCI: Cyanocobalamin, Methylcobalamin
Category: Vitamin, skin-support nutrient
Used in: Skincare, supplements
Typical Usage Level (Topical):
0.01% – 0.1% in leave-on skincare formulations

Typical Usage Level (Oral Supplements):
2.4 mcg per day for general nutritional support
Higher doses may be used under medical guidance.

What This Ingredient Does

Vitamin B12 is a water-soluble vitamin involved in DNA synthesis, red blood cell formation, and cellular energy metabolism. These processes are important for maintaining healthy skin function and supporting normal cell turnover.

In dermatology, adequate vitamin B12 levels contribute to healthy skin repair and overall skin vitality. Deficiency can sometimes manifest as skin changes, including hyperpigmentation, cracks around mouth corners, or inflammation.

Topically, vitamin B12 is used in some formulations for its soothing and skin-supportive properties, particularly in products designed for sensitive or compromised skin.

Key Benefits

  • Supports healthy skin cell turnover
  • Contributes to normal skin repair processes
  • Helps maintain overall skin vitality
  • Provides supportive care for sensitive or stressed skin
  • Plays an important role in overall nutritional skin health

Who It’s Best For

  • Individuals with nutritional deficiencies affecting skin health
  • Skin experiencing dryness or reduced vitality
  • Sensitive or stressed skin needing supportive care
  • Those seeking overall skin health support

Clinical Note by Dr. Su

M.D. Dermatologist

Vitamin B12 is an important nutrient for overall skin and systemic health. While topical use offers supportive skin benefits, maintaining adequate dietary intake is essential for proper skin repair and cellular function.

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